

A day without a latte, cup of tea,
or caffeinated soft drink is unthinkable for many people. Yet caffeine
poses some health risks. Although individuals seem to differ in their
vulnerability to caffeine’s influence, if drunk in moderation, the risks
appear negligible.
Studies on caffeine discount any risk of cancer. A major report from
the American Institute for Cancer Research, based on numerous studies,
concluded that coffee has no link to cancer risk.
Drinking more than four cups of coffee a day, however, may increase
the risk of heart problems. In fact, a new study suggests that even
two six-ounce cups of coffee a day may increase blood test values that
measure inflammation.
If future research confirms these findings, there may be cause for concern.
But it’s too early to severely limit your coffee consumption for this
reason, because two large American studies show no effect of coffee
or caffeine on the incidence of heart disease.
Osteoporosis Warning
Earlier research seemed to show that caffeine increases the loss of
calcium, raising the risk of osteoporosis. Even in a fairly recent study,
women aged 65-77 who drank more than 300 milligrams (mg) of caffeine
daily — about 18 ounces of regular coffee — showed greater bone loss
over a three-year period than those who drank less. But the bone loss
occurred only among a minority of women with an unusual variation in
their cell vitamin D receptors.

SCIENTISTS FOCUS ON COLOR TO IMPROVE BENEFITS
Research that has focused on making tomatoes disease resistant
and easier to ship could also one day improve their taste and make them more
nutritious, researchers say.
At Ohio State University, scientists are working with seeds from hundreds
of tomato plants to learn more about how a tomato’s color can improve its
nutritional value.
“Their appearance may be uniform, but as you dive down deeper you find they
are quite different,” said David Francis, who breeds tomato seeds. “One gene
can make all the difference.”
Jay Scott, a breeder at the University of Florida, has spent seven years studying
how to improve flavor through taste tests and genetic analysis.
Scott said many factors influence taste, including the tomato’s balance of
sugar and acid. He said producers first want a tomato that resists diseases
and ships easily.
“I don’t think anybody’s against better flavor,” Scott said. “It’s a question
of can they do that and provide everything else.”
Francis noted that breeding has created more diverse tomatoes, with most supermarkets
today carrying grape, cherry, roam, beefsteak, cluster and hydroponic tomatoes.
The research also has made tomatoes that are less expensive to produce and
purchase.
Advances include tomatoes that ripen after they’re picked, so they can survive
on longer shipping routes; are firmer, to withstand bruising during shipment;
and are more resistant to fungus and bacteria.
The biggest complaint about the modern tomato is lack of taste. Consumers
say today’s varieties are not as juicy or sweet and they sometimes blame the
breeders.
Taste tests show that some new varieties rate better than heirloom tomatoes
despite a popular opinion that older is better, Scott said.
“I’m not sure if the public has been dumbed down so much that they don’t know
what tomatoes are supposed to taste like,” he said.
The different shapes, colors and sizes created by breeding are mainly designed
to catch the eye of the shopper, a development that has come at a time when
tomato consumption has risen steadily in the last four decades.
Americans eat about 92 pounds of tomatoes annually in everything from ketchup
to pasta sauces and salsa, according to a report from the U.S. Department
of Agriculture released in 2000. The report attributed the climb to interest
in Italian and Mexican food and awareness of the tomato’s health benefits.
Tomatoes are an excellent source of lycopene, which fights some types of cancers,
including prostate cancer, and beta-carotene, or pro-vitamin A, which is important
for the eyes.
Francis said not enough is known to say whether new varieties of tomato, such
as the cherry tomato, are more or less nutritious.
One way to develop a more nutritious tomato would be to solve what causes
the fleshy part of some tomatoes to turn yellow, researchers say.
Ohio State student researcher Audrey Darrigues hopes the wild tomatoes in
the university’s greenhouse will provide a resistant gene that will ward off
the color disorder.
“Color is a very important element in the tomato,” she said.
Dear
Dr. Mirkin:
If cooking destroys nutrients,
shouldn’t we eat only raw foods?
Raw fruits and vegetables have many phytochemicals that help to keep you healthy,
but those frozen soon after harvest may have higher levels of phytochemicals
than those that take days or weeks to be transported to your supermarket.
Frozen and cooked vegetables can be just as healthful as fresh ones.
Many people believe that fresh fruits and vegetables always contain more nutrients
than cooked ones, but cooked carrots have higher levels of antioxidants than
fresh carrots. Cooking carrots in the presence of a small amount of oil or
butter increases the amount of two antioxidants called beta carotene and phenolic
acid. Cooking also increases the amount of lycopene you get from tomatoes.
Cooking breaks the plant cells open to increase the absorption of these antioxidants
and other beneficial plant chemicals. Adding a little oil or butter increases
absorption of fat-soluble chemicals.
Some vitamins may be lost in cooking, but you still get plenty if you have
a reasonably varied diet. The enzymes in food that are destroyed by heat are
of no use to you; you make your own enzymes for digestion of your food. Most
of the nutrients in your food (minerals, proteins, fats, carbohydrates) are
not destroyed by heat, and many common foods are unpalatable or unsafe if
they are not cooked. I recommend eating the widest possible variety of fruits
and vegetables, raw or cooked, and fresh, frozen, canned or dried.
This health info is provided with the permission of Dr. Gabe Mirkin, M.D.
Dr. Mirkin has practiced medicine for more than 40 years and is board-certified
in four specialties: Allergy and Immunology, Sports Medicine, Pediatrics and
Pediatric Immunology. Visit www.drmirkin.com.
Eating
Eggs Okay for the Healthy Heart
In
healthy adults, consuming two eggs daily for 6 weeks does not have a harmful
effect on endothelial function – an aggregate measure of cardiac risk – nor
does it increase cholesterol levels, research shows. This suggests that eating
eggs may not be as bad for the heart as many people contend.
Because of the cholesterol content of eggs, limiting their consumption is
generally recommended as a way to reduce cardiac risk, say the investigators.
However, emerging evidence suggests that dietary cholesterol has a much smaller
effect on this risk than does saturated fat.
Dr. David L. Katz and colleagues, from the Yale Prevention Research Center
in Derby, CT, evaluated the effect that egg or oat consumption had on endothelial
function in 49 healthy adults. Poor endothelial function is suspected of being
an early sign of artery disease.
During the study period, flow-mediated dilation (FMD), a measure of how well
the endothelium, the lining of the blood vessel, acts to keep blood moving
by widening the vessel, was stable in both groups and did not differ significantly
between them.
Egg intake did not cause an increase in either total or LDL cholesterol levels.
By contrast, oat consumption significantly lowered levels of both.
“Usually, people are saying ‘you can’t eat this or you can’t eat that,’” Katz
told reporters. “It’s nice to have findings that exonerate a food, like eggs.”
Nevertheless, this may not be the case in patients who already have elevated
lipids, a group at increased risk for endothelial dysfunction. “We’ve now
started a study of adults with hyperlipidemia,” Katz added, “to determine
if the current results apply to this group as well.”
The study was funded, in part, by the American Egg Board.
SOURCE: International Journal of Cardiology March 10, 2005.
Forget the Breath
Mints,
EAT YOGURT INSTEAD
New study findings suggest that yogurt
may be another weapon in the battle against bad breath.
“Yogurt intake may improve oral hygiene, namely tongue-coating bacteria and
halitosis,” study author Dr. Kenichi Hojo of Tsurumi University in Yokohama,
Japan told reporters.
He and his colleagues found that study participants who consumed 90 grams
of yogurt twice a day for six weeks tended to have lower levels of hydrogen
sulfide and other volatile sulfide compounds that contribute to bad breath.
They presented their findings during the 83rd General Session of the International
Association for Dental Research held in mid-March in Baltimore.
Previous studies have also pointed to the benefits of regular yogurt consumption.
One report found that women who ate yogurt at least three times a week were
less likely to have recently developed a urinary tract infection than women
who ate such probiotic bacteria-containing foods less than once a week.
Other studies have found that yogurt plays a role in the prevention and management
of bowel disease and other gastrointestinal conditions. Furthermore, another
study showed that people who eat yogurt regularly might have a lower risk
of cavities.
Hojo and his team also have not yet determined how or why yogurt consumption
had such an effect on halitosis. “In the future,” he said, “I will focus on
the mechanism of that effect.”

“SuperFood”
OF THE MONTH:TOMATOES!
A “fruit” rich in antioxidant lycopene; contains two powerful compounds
(coumaric acid and chlorogenic acid) that may help block the effect of nitrosamines
(cancer-causing compounds); rich in vitamins A and C.
INGREDIENTS:
15 tomatoes, peeled and chopped
5 fresh peaches - peeled, pitted and chopped
5 red apples - peeled, cored and diced
4 medium onions, diced
4 stalks celery, diced
1 1/2 cups golden raisins
1 1/2 cups distilled white vinegar
1 Tbsp salt
1 cup pickling spice, wrapped in cheesecloth
TO MAKE:
Combine the tomatoes, peaches, apples, onions, celery, raisins, vinegar, salt
and pickling spice in a large stockpot. Bring to a boil, then reduce heat
to low and simmer for about 2 hours, or until thickened. Store in the refrigerator,
or freeze in plastic containers. Makes 8 cups.

Nutrition Info Per Serving (Servings Per Recipe: 64) Cal: 21, Total Fat:
0.2g, Chol: 0mg, Sodium: 114mg, Total Carbs: 5g, Dietary Fiber:0.9g, Protein:
0.4g


In fact, high caffeine consumption only seems to cause bone
loss in elderly women who don’t get enough calcium. As long as elderly women
get the recommended 1,200mg of calcium a day, it should be safe for them to
drink up to 300mg caffeine, or about 18 ounces of coffee or its equivalent.
Caffeine does not appear to adversely affect the bones of premenopausal women
at all.
At one time, some consumer advice claimed that caffeinated drinks deplete
the body’s fluid levels because caffeine increases urination. More recent
research shows that a person’s fluid balance is not significantly affected
by a moderate use of caffeine.
Bad for High Blood Pressure?
Since some studies suggest that two to three cups of coffee can raise blood
pressure around 10 points, many physicians limit people with high blood pressure
to 200mg (two six-ounce cups of coffee) per day or less. However, regular
caffeine consumers may develop a caffeine tolerance that prevents blood pressure
elevations, according to other studies.
The greatest reason people drink caffeinated beverages is to increase their
energy and alertness. Studies show that 100 to 200mg of caffeine (about 1
to 2 cups of regular coffee) are enough to achieve these results. When caffeine
consumption climbs to 250-700mg per day, people may experience nausea, headaches,
sleep difficulties or increased anxiety. People may have heart palpitations
with more than 1,000mg.
Some day, there may be individual advice for everyone about how much caffeine
they can safely consume. Research, however, is only beginning to explain why
caffeine’s influence varies so much. For instance, genetic differences in
the enzymes that metabolize caffeine cause some people to process caffeine
quickly, thus reducing their exposure to caffeine’s effects sooner. There
are also inherited differences in cell receptors.
For now, you should stick to moderate amounts of caffeine. For an adult, that
means no more than 300mg daily, which is three 6-ounce cups of coffee, four
cups of regular tea, or six 12-ounce colas.
A person may want to have even less, depending upon how caffeine affects their
sleep, blood pressure, digestive system and overall well-being. Children,
nursing mothers or pregnant women, on the other hand, should have much less
because caffeine will have stronger effects in smaller bodies.
WHAT’S IN THAT WEIGHT
LOSS SUPPLEMENT?
Many common ingredients pose potential health
risks
Americans spend billions of dollars each year on weight-loss
supplements. Although we wouldn’t buy a car or a dinner without knowing some
details, many who purchase these supplements have no idea what is in them,
or what independent reports say about their safety and effectiveness.
Even though the Food and Drug Administration has charged some companies with
using banned ingredients, and the Federal Trade Commission has successfully
prosecuted marketers who made illegal claims, the same products, or copycat
versions, still remain available.
Some weight loss supplements contain ingredients meant to suppress the appetite.
Caffeine and its herbal counterparts, guarana, bitter orange and yerba maté,
as well as ephedra (ma huang), fall into this category. Animal studies suggest
that they may slightly suppress the appetite, but the limited human studies
lasted only a few months. All these ingredients are nervous system stimulants,
so they commonly produce side effects like headaches, insomnia, elevated blood
pressure and heart palpitations.
Deceptive Labeling
Product labeling can be deceptive: Weight-loss supplements labeled ephedra-
or caffeine-free may contain other ingredients from the list above, which
may pose the same health risks. Although ephedra (ma huang) has been banned
by the FDA, you may still see it in some supplements. In a summary of more
than 50 trials, this substance created a 2 to 3.6-fold increase in the risk
of psychological, heart and digestive system problems.
Supplement manufacturers claim other ingredients aid weight loss by speeding
up the metabolism. For example, EGCG, a phytochemical found in green tea,
is being studied for its potential to reduce cancer risk. Some initial studies
suggest it could slightly increase the rate at which calories burn. Now it
can be found in many weight-loss supplements and “weight-loss vitamins.”
However, since there are only extremely short initial studies so far, the
body might adapt to EGCG, reducing its effect over time. In addition, the
weight loss benefit seen with EGCG amounts to about 60-70 calories a day.
This small difference is more likely to help prevent a gradual yearly weight
gain than reverse excessive weight gain. Third, the effect of EGCG appears
to depend on the dose. Supplements with amounts of 30-40mg of EGCG, which
is commonly seen in these products, may not have the same effect as a dose
over 250mg used in the studies.
Few Significant Effects
Supplements may also contain ingredients that manufacturers state will block
the absorption of fat or carbohydrates. Chitosan is a common example, and
a few preliminary studies made it appear promising. However, several controlled
studies found that chitosan had no significant effect on fat absorption. In
the most recent study, men would need seven months to lose one pound of body
fat. There was no fat loss for women.
Another group of ingredients are said to increase the feeling of fullness
and decrease eating. Guar gum appears safe for this purpose, but 11 well-controlled
studies show it has no benefit for weight loss. Psyllium can help control
blood sugar and blood cholesterol, but studies do not support its reputed
ability to reduce eating and assist weight loss.
There are more than 50 individual supplements and 125 combination products
now available for people who want to lose weight. Yet a Harvard Medical School
review of these products that set standards for product quality, safety and
effectiveness concluded that none of them met all three standards.
Future research may identify some safe and effective ingredients for weight
loss, but for now it seems smarter to invest in walking shoes, a gym membership,
or healthier food instead.
Dear
Dr. Mirkin:
Are colon cleansers necessary for good
health?
No. The latest research shows that regular use of laxatives
or colon cleansers can harm you by
blocking the absorption of nutrients from your colon into your bloodstream.
There are two absorption systems in the digestive tract. First, the food that
you eat passes from your stomach to your upper intestines, where secretions
from your stomach, liver, intestines and pancreas break down carbohydrates,
fats and proteins into their building blocks. Only these building blocks –
basic sugars, amino acids, fatty acids and glycerol – are absorbed from your
intestines into your bloodstream. The food that is not broken down cannot
be absorbed, so it passes to your colon.
Bacteria in your colon convert undigested starches into short-chain fatty
acids that heal ulcers, prevent colon cancer and other cancers, reduce the
pain of arthritis, prevent the arterial damage of arteriosclerosis, lower
cholesterol, and even lower high blood pressure. Regular use of colon cleansers
or laxatives reduces the absorption of these beneficial short-chain fatty
acids.
People who recommend these products claim that they remove old feces that
get stuck and rot in your colon, but this is ridiculous. Undigested waste
products stick together by a physical process called surface tension, so they
cannot pass by older stool. Colon cleansers not only have not been shown to
help you, they can harm you by depriving you of nutrients that are necessary
for health.
This health info is provided with the permission of Dr.
Gabe Mirkin, M.D. Dr. Mirkin has practiced medicine for more than 40 years
and is board-certified in four specialties: Allergy and Immunology, Sports
Medicine, Pediatrics and Pediatric Immunology. Visit www.drmirkin.com
